Multilocus Sequence Typing System for Group B Streptococcus

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Multilocus sequence typing system for group B streptococcus.

A multilocus sequence typing (MLST) system was developed for group B streptococcus (GBS). The system was used to characterize a collection (n = 152) of globally and ecologically diverse human strains of GBS that included representatives of capsular serotypes Ia, Ib, II, III, V, VI, and VIII. Fragments (459 to 519 bp) of seven housekeeping genes were amplified by PCR for each strain and sequence...

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Multilocus sequence typing of invasive group B Streptococcus in central area of Taiwan.

BACKGROUND Group B Streptococcus (GBS) (Streptococcus agalactiae) is an important pathogen in neonates, pregnant women, and adults with underlying disease. METHODS Fifty clinical isolates were collected during the period 2001-2004 and analyzed by multilocus sequence typing and capsular serotyping. RESULTS The six major sequence types (STs) identified by multilocus sequence typing were ST1, ...

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Serotype III group B streptococcus (GBS) causes more invasive disease in infants than do other serotypes in North America. We used multilocus sequence typing to identify clones within 28 invasive serotype III GBS isolates identified from a population-based study and 55 serotype III GBS colonizing isolates from a cohort of women from the same population. Ten allelic sequence types (STs) were ide...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2003

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.41.6.2530-2536.2003